Champion Kerber is outclassed by Coco

The top two men - Andy Murray and Novak Djokovic - and three of the top four women - Kerber, Aga Radwanska and Simona Halep - have departed in the Open's first week.

World No35 Vandeweghe overpowered the German 6-2, 6-3 to claim the biggest win of her career and set up a quarter-final with Spain's Garbine Muguruza.

"I faked it a lot because I was feeling like crap out there... what do they say, "fake it until you make it"?", she said. EPA/DEAN LEWINSCoco Vandeweghe of US celebrates after winning her Women's Singles fourth round match against Angelique Kerber of Germany at the Australian Open Grand Slam tennis tournament in Melbourne, Victoria, Australia, 23 January 2017.

Facing the ultra-consistent Kerber, Vandeweghe refused to play the waiting game. "She is going to play that way, and no other way", Vandeweghe said.

Hitting 30 winners to seven, the 25-year-old completely exasperated Kerber, who was powerless and showed it.

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This contest should go the distance, but whether Vandeweghe can cause a boilover will rest on her ability during clutch moments. Vandeweghe sent down an ace down the tee for her first match point, and at the first time of asking, the upset was complete with a backhand error from Kerber.

"This is what you do all the hard work in the off-season for", she said. "We're two totally opposite players".

Should he get past France's Monfils, he will face either No. 3 Milos Raonic (now the highest-ranked male remaining) or No. 13 Roberto Bautista Agut in the quarterfinal.

"Going out there and playing an opponent, any opponent, I go out there expecting to win", she said.

In a post-match news conference, Kerber said: "It was a tough match, and of course I'm disappointed". While her first serve was erratic - she made just 51 per cent during the match - it was potent, good for 21 of 27 points played off her first delivery. She was up a break in the second set and looked to be regaining control of the match, but Vandeweghe came charging back with pinpoint forehand winners that Kerber just watched go by. "Fake it till you make it".

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Pavlyuchenkova is into her first quarters at the Australian Open.

With Murray and the Serbian reigning champion having already departed, Melbourne Park will next week witness the first grand slam since the 2004 French Open without its top two men's seeds. Unseeded Vandeweghe upset the defending Australian Open champion, 6-3, 6-2. Murray lost to unheralded German Mischa Zverev and Kerber to up and coming American Coco Vandeweghe.

Murray was stunned by 50th-ranked serve-and-volley specialist Mischa Zverev in four sets before Kerber, the women's title-holder, tamely succumbed 6-2, 6-3 to Coco Vandeweghe.

Federer will hope to profit as he bids for his 18th grand slam title, as will his compatriot and 2014 champion Stan Wawrinka, who is in the same half of the draw and fended off Andreas Seppi 7-6 (2) 7-6 (4) 7-6 (4).

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