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The top two men - Andy Murray and Novak Djokovic - and three of the top four women - Kerber, Aga Radwanska and Simona Halep - have departed in the Open's first week.
World No35 Vandeweghe overpowered the German 6-2, 6-3 to claim the biggest win of her career and set up a quarter-final with Spain's Garbine Muguruza.
"I faked it a lot because I was feeling like crap out there... what do they say, "fake it until you make it"?", she said. EPA/DEAN LEWINSCoco Vandeweghe of US celebrates after winning her Women's Singles fourth round match against Angelique Kerber of Germany at the Australian Open Grand Slam tennis tournament in Melbourne, Victoria, Australia, 23 January 2017.
Facing the ultra-consistent Kerber, Vandeweghe refused to play the waiting game. "She is going to play that way, and no other way", Vandeweghe said.
Hitting 30 winners to seven, the 25-year-old completely exasperated Kerber, who was powerless and showed it.
This contest should go the distance, but whether Vandeweghe can cause a boilover will rest on her ability during clutch moments. Vandeweghe sent down an ace down the tee for her first match point, and at the first time of asking, the upset was complete with a backhand error from Kerber.
"This is what you do all the hard work in the off-season for", she said. "We're two totally opposite players".
Should he get past France's Monfils, he will face either No. 3 Milos Raonic (now the highest-ranked male remaining) or No. 13 Roberto Bautista Agut in the quarterfinal.
"Going out there and playing an opponent, any opponent, I go out there expecting to win", she said.
In a post-match news conference, Kerber said: "It was a tough match, and of course I'm disappointed". While her first serve was erratic - she made just 51 per cent during the match - it was potent, good for 21 of 27 points played off her first delivery. She was up a break in the second set and looked to be regaining control of the match, but Vandeweghe came charging back with pinpoint forehand winners that Kerber just watched go by. "Fake it till you make it".
Pavlyuchenkova is into her first quarters at the Australian Open.
With Murray and the Serbian reigning champion having already departed, Melbourne Park will next week witness the first grand slam since the 2004 French Open without its top two men's seeds. Unseeded Vandeweghe upset the defending Australian Open champion, 6-3, 6-2. Murray lost to unheralded German Mischa Zverev and Kerber to up and coming American Coco Vandeweghe.
Murray was stunned by 50th-ranked serve-and-volley specialist Mischa Zverev in four sets before Kerber, the women's title-holder, tamely succumbed 6-2, 6-3 to Coco Vandeweghe.
Federer will hope to profit as he bids for his 18th grand slam title, as will his compatriot and 2014 champion Stan Wawrinka, who is in the same half of the draw and fended off Andreas Seppi 7-6 (2) 7-6 (4) 7-6 (4).
A Trump wax figure has been in the lobby of the Ripley's Believe It or Not on International Drive for the past month. On Wednesday, Madame Tussauds' London location unveiled its official wax figure of the President-elect.
But many analysts have ignored the effect of low oil prices on other countries outside of the United States and OPEC. The year "2017 will include an inflation on the cost of doing business", the Saudi oil minister said.
NY state issued new regulations Saturday that require insurers to provide contraceptives without any cost sharing to patients. Directs agencies to grant greater flexibility to the states and cooperate with them in implementing healthcare programs.
Jackson obtained the Beatles songs as part of a larger trove of some 4,000 pop tunes from Australian businessman Robert Holmes. This was the basis of Duran Duran's attempt to terminate Sony/ATV's ownership of their songs in the UK High Court in December.
ESPN's Jeff Goodman reports the sophomore guard's suspension stems from a failed test for a performance-enhancing drug. He's remained on Arizona's bench throughout the season but coach Sean Miller never gave clarity to the situation.
Autosteer is intended for use on highways with clear lane markings and maintains position within the lane in slow-moving traffic. This update includes the new Forward Collision Warning feature, Traffic-Aware Cruise Control (TACC), and Low-Speed Autosteer.
The Recording Academy announced Friday that Adele will perform at the February 12 show at the Staples Center in Los Angeles . Adele is also a pal of Grammy host James Corden; her installment of his Carpool Karaoke is the most-viewed of all time.
The presidents of Guinea and Mauritania were locked in talks with Mr Jammeh for hours on Friday negotiating his future. But around 6pm local time today (Jan.20), the defeated president finally agreed to step down.
Russian and Syrian forces have been unsuccessful in their attempts to hold the city after pushing ISIS militants out in March. The group is known to have destroyed other monuments before they were forced out by a Russian-backed government offensive.
Iranian firefighters work to extinguish fire of the Plasco building before it collapsed, January 19, 2017. The 50-year-old Plasco, home to a major shopping centre, was one of Tehran's most recognisable landmarks.
To go along with the release date, and the new trailer, Namco also revealed pre-order details and a collector's edition. The Six Edition comes with a 10cm high figurine, an exclusive A3 poster, and a sticker board, as well as the soundtrack.
Individual income tax filing season begins in MI
Last year, more than 4 million MI taxpayers e-filed and had their refunds directly deposited into their bank accounts. All individual income tax returns must be e-filed or postmarked by Tuesday, April 18, 2017.
Scott Pruitt is an Environmental Disaster in the Making
He was quoted in a Montana newspaper as saying that manmade climate change was "not a hoax, but it's not proven science either". Pruitt is expected to face tough questioning about his stance on climate change and ties to the oil and gas industry.
3 bids from China for West Ham departee PAYET
Dimitri Payet remains in limbo at West Ham but manager Slaven Bilic is hopeful of making a new signing within the next 24 hours. Ahead of the Gunners' clash with Burnley on Sunday, Wenger said: "I don't need Payet because we have so many creative players".
New North Korea ICBMs captured by intelligence, report says
The devices "are estimated to not exceed 15 meters (50 feet) in length, making them shorter than the North's existing ICBMs". North Korea is understood to be able to process plutonium at the Yongbyon site for use in potential nuclear warheads.
Vikrant proposes Mona Lisa Antara to marry her!
During the ceremony, the contestants are asked to perform all rituals and have been given a task of making it entertaining. Since Vikrant is also staying inside the house till the wedding, his Haldi ceremony also took place along with Mona .